Jinan Hongyuan Chemical Co.,Ltd
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Lipoic Acid, also known as α- Lipoic acid (LA or ALA), with the molecular formula of C8H14O2S2, is an organic compound that is fat soluble, and the reduced dihydrolipoic acid (DHLA) is water-soluble.
Lipoic acid is one of the most effective natural antioxidants known. Its antioxidant capacity is 400 times that of VC, 60 times that of VE, 10 times that of lycopene, and also higher than that of grape seed extract, anthocyanin, etc.
Lipoic acid can eliminate free radicals and regenerate endogenous antioxidants, such as VC, VE, Coenzyme Q10, Glutathione and lipoic acid itself. In addition, it can also coordinate with metal ions, such as iron, copper, mercury, etc., so as to inhibit the free radical reaction catalyzed by metal ions and reduce tissue damage.
Regulate glucose metabolism and improve diabetic complications
It can regulate glucose metabolism and improve the formation of advanced glycation end products (AGE) caused by diabetic complications hyperglycemia, which can induce the production of a large number of reactive oxygen free radicals. Lipoic acid can clear active free radicals, reduce oxidative stress, and protect the pancreas β Cells are not damaged by oxygen free radicals. Lipoic acid can also reduce a variety of inflammatory factors, alleviate oxidative stress, improve serum creatinine and urea nitrogen levels in patients with diabetic nephropathy, and effectively prevent renal failure.
Some European countries use it as a nutritional supplement. The commonly used dose for adults is 200-600mg/d. It is clinically recommended that the adjuvant dose for diabetes is 300-600mg/d, and the dose for general population in private rooms is 20-50mg/d. At present, lipoic acid is a prescription drug for the treatment of diabetic neuropathy in Germany.
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