Triethylamine CAS No 121-44-8

Triethylamine CAS 121-44-8

Use of Triethylamine

Triethylamine is the simplest homogeneous trisubstituted tertiary amine that is liquid at room temperature, so it is widely used as a solvent and base in organic synthesis. It is one of the most commonly used organic bases in organic synthesis. The boiling point is around 89 degrees Celsius, which is relatively easy to remove by distillation. The solubility of its hydrochloride and hydrobromide in Organic Solvents such as ether is not very high, so it can sometimes be separated directly by filtration. The simpler trimethylamine is a colorless gas under normal conditions and must be stored under pressure in a gas tank or stored in the form of a 40% Aqueous Solution. It is not as easy to use as triethylamine. 

Triethylamine can be used for elimination reactions such as Swern oxidation reaction, dehydrohalogenation reaction, Heck reaction, silanol ether preparation reaction, ester and amide preparation reaction from acid chloride, as well as protecting groups for hydroxyl, carboxyl and amino groups. When the basic catalyst. It reacts with hydrochloric acid to obtain triethylamine hydrochloride, and reacts with alkylating reagent to obtain the corresponding quaternary ammonium salt. 
Triethylamine is used in the manufacture of medicines, pesticides, polymerization inhibitors, high-energy fuels, rubber vulcanizing agents, etc. 
It can be used as a solvent, catalyst and raw material in the organic synthesis industry. 
It can be used to prepare phosgene process polycarbonate catalyst, tetrafluoroethylene polymerization inhibitor, rubber vulcanization accelerator, special solvent in paint remover, enamel anti-hardening agent, surfactant, preservative, penetrant, waterproof Agents, bactericides, ion exchange resins, dyes, fragrances, medicines, high-energy fuels and liquid rocket propellants, etc. 
The products that consume triethylamine in the Pharmaceutical industry include: Ampicillin Sodium, Amoxicillin, Pioneer IV, Cefazolin Sodium, Cefradine, Oxypiperazine, Ketoconazole, Vitamin B6, Fludixic Acid, Praziquantel , Thiotepa, penicillamine, berberine hydrochloride, verapamil, o-chlorophenylacetic acid and pipemidic acid, etc.

Triethylamine CAS 121-44-8

Index Terms

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