What is Lipoic acid?
2022-12-06
Lipoic Acid is an endogenous antioxidant, which can remove free radicals, promote the synthesis of vitamin C from glucose, promote the synthesis of Glutathione, effectively remove melanin, and assist coenzymes in physiological metabolism conducive to immunity. Lipoic acid also has anti-inflammatory effect, can inhibit the activities of kinase, transforming factor, tumor necrosis factor and collagenase, and has anti-aging effect. Lipoic acid can preserve and regenerate other antioxidants and has a good health function to human body. It is widely used in the prevention and treatment of heart disease, diabetes, Chemicalbook liver disease and Alzheimer's disease. The two enantiomers of lipoic acid show different biological activities. The R-type enantiomer is much more effective than the S-type, which may be due to the fact that during the metabolism of lipoic acid, a large amount of R-type lipoic acid can enter cells and mitochondria through cell membrane and mitochondrial membrane and be reduced to dihydrolipoic acid, while only a small amount of S-type can enter cells and be reduced. Dihydrolipoic acid has stronger antioxidant capacity than lipoic acid. The regeneration of endogenous antioxidants and the repair of oxidative damage can only be realized in the form of dihydrolipoic acid.
