Glipizide for type 2 diabetes CAS NO 29094-61-9

Chemical Raw Material Glipizide CAS 29094-61-9 

Effect:

Glipizide is the second generation sulfonylurea oral hypoglycemic agent. It mainly promotes the secretion of insulin by islet beta cells, especially the secretion of insulin β cells stimulated by glucose; it also enhances the effect of insulin, so as to effectively reduce blood glucose concentration and glycosylated hemoglobin; it can improve hyperlipidemia, reduce triglycerides and cholesterol levels, increase the ratio of high-density lipoprotein cholesterol in total cholesterol; it can also inhibit platelet aggregation And promote fibrinolysis, which may have a certain preventive and therapeutic effect on vascular disease. ① To promote insulin secretion of pancreatic islet β cells, the prerequisite is that islet β cells have a certain function of insulin synthesis and secretion; ② by increasing the level of portal vein insulin or directly acting on the liver, inhibiting glycogen decomposition and gluconeogenesis, reducing the production and output of glucose in the liver; ③ it may also increase the sensitivity of extrapancreatic tissues to insulin and the utilization of glucose (may Therefore, the total effect is that the pharmacokinetic absorption is fast. The blood concentration reaches the peak at 1-2.5 hours after oral administration, and the duration of action can reach 24 hours, and T1 / 2 is 2.5-4 hours. 97% of them were discharged from the body on the first day and 100% on the second day.

Company profile:
Mingya trading Private Limited (also known as: Jinan Hongyuan Chemical Co., Ltd., responsible for domestic trade) is a comprehensive trading company specializing in chemical Solvents, chemical additives, pharmaceutical intermediates, API and other products. Since its establishment for 13 years, the company has won high recognition from customers at home and abroad with its rigorous, pragmatic and honest management style. We have established long-term and close cooperation with hundreds of customers in more than 10 countries and regions.
 
The company's advantages in the supply of Chemical Products such as Methylcyclohexane, Cyclohexane, Cyclohexanone, Chloroethene, DL-Lipoic Acid, Ethyl 6,8-dichlorocaprylate, phenylhydrazine, 2-(4-Bromomethyl)phenylpropionic acid, Aromatic amine ， vinylidene chloride, and other raw materials and Intermediates make the products of high quality and excellent service.
 
Why choose us:
1. We have the resources of the manufacturer, the product quality is good, the price is low, and the delivery is timely.
2. We have a mature service team with rich experience in import and export trade.
3.We have a wide range of customers and strong product sourcing ability.