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Model No.: 29122-68-7
Brand: Mingya
Packaging: 25kg/Drum
Productivity: 5000mt One Year
Transportation: Ocean,Land,Air
Place of Origin: China
Supply Ability: 1000kg
Certificate: state-owned enterprise
HS Code: 2924299090
Port: Shanghai,Qingdao
Payment Type: L/C,T/T,D/P,Paypal,Money Gram
Incoterm: FOB,CFR,CIF,FCA,CPT
Chemical Raw Material Atenolol CAS 29122-68-7
purpose:
Atenolol is a selective β 1-adrenoceptor antagonist.
effect:
This drug is a long-acting and selective β 1-adrenoceptor blocker. Its cardiac selectivity is significantly stronger than metoprolol, but its inhibition on β 2 receptor of vascular and bronchial smooth muscle is weak. There was no endogenous sympathetic activity, no membrane stability and no inhibition of myocardial contractility. This product can reduce the blood pressure of patients with hypertension and reduce the increase of blood pressure caused by exercise. At the same time, reduce the heart rate (8% - 34%) and the product of heart rate and blood pressure (9% - 40%), reduce the severity and frequency of angina pectoris, and improve the oxygen consumption index of patients with acute myocardial infarction. Therefore, early application of the drug can reduce the size of myocardial infarction and prevent reinfarction, and long-term application can reduce the mortality of myocardial infarction or stroke.
After oral administration, the absorption rate was 50% - 60%, and the peak time of blood drug was 2-4 H. The bioavailability was about 60%, the plasma protein binding rate was about 46%, and the apparent distribution volume was 0.8l/kg. It is widely distributed in the body, a small amount of it enters the brain, can quickly pass through the placenta, and can accumulate in the milk, but the concentration of the drug in the baby's blood is very small. In adult patients with normal renal function, the elimination half time is about 5-7 hours, and the total clearance rate is about 6 L / h (100 ml / min). The half time of clearance in children was shorter (4,5 h). About 46% of the absorbed drugs were excreted from the urine in the original form. The clearance rate decreased in patients with abnormal renal function, which was mainly related to glomerular filtration rate.
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Name: | Atenolol |
Cas No: | CAS 29122-68-7 |
MF: | C14H22N2O3 |
Appearance: | White Powder |
purity: | >99% |
Brand Name: | Ming ya |
Delivery time: | Within 1-3 days payment |
Export Markets: | Global |
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Product Categories : Fine Chemicals > Water Treatment Agent
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Privacy statement: Your privacy is very important to Us. Our company promises not to disclose your personal information to any external company with out your explicit permission.